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Velasof Tablet
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Velasof Tablet

₹20,855.00 Original price was: ₹20,855.00.₹5,999.00Current price is: ₹5,999.00.

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  • Velpatasvir (100 mg)
  • Sofosbuvir (400 mg)
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About Velasof Tablet

Salt : Velpatasvir (100 mg) + Sofosbuvir (400 mg)

Product Introduction

Velasof Tablet is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection.

Velasof Tablet should be taken in the prescribed dose and duration. It can be taken with or without food, but take it at the same time daily. It is advised not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver or kidney disease. It is harmful to consume alcohol along with this medicine, so it is advised to limit or avoid alcohol. The course of the medicine should be completed for better results.

The common side effects of this medicine include fatigue, anemia, nausea, headache, insomnia, and diarrhea. You should drink plenty of fluid and eat a healthy diet to prevent or overcome the side effects. Before taking the medicine, inform your doctor if you are taking any other medicines or supplements.

Velasof tablet contains the active components Sofosbuvir and Velpatasvir.  It is used to treat chronic hepatitis C. Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). The treatment duration is often shorter than older treatment regimens. The duration can vary depending on factors such as HCV genotype, previous treatment history, and the presence of liver cirrhosis. Successful treatment with Velasof tablet can significantly reduce liver inflammation and fibrosis caused by HCV infection. By achieving viral eradication, the risk of developing liver cirrhosis, liver failure, and hepatocellular carcinoma (a type of liver cancer) can be substantially reduced.

If you have a known allergy or hypersensitivity to Velasof tablet or any of the components of the medication, you should not take it. The safety and efficacy of sofosbuvir and velpatasvir combination therapy have not been established in children under 18. Its use in the pediatric population is currently limited. It is recommended to use alternative treatment options or adjust the dosage in these cases.

Benefits of

In Treatment of Chronic hepatitis C virus (HCV) infection

Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). When the infection moves into a long-lasting stage, it is called chronic hepatitis C virus infection. Velpanat Tablet helps reduce the number of hepatitis C virus by preventing it from spreading in your body. This helps control the infection and helps you recover faster. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor.

Side effects of  Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of

  • Headache
  • Tiredness
  • Diarrhea

How to use Velasof Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Velpanat Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Velasof Tablet works

Velpanat Tablet is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

Uses of Velasof Tablet

  • To treat chronic hepatitis C (HCV) infection.

Therapeutic Effects of Velasof Tablet

Sofosbuvir is a direct-acting antiviral drug (DAA) that inhibits the replication of the HCV virus by targeting a specific protein necessary for viral replication. Velpatasvir is also a DAA that works by blocking the action of another protein involved in the HCV replication process.


Interaction of Velasof Tablet with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Velasof tablet, reducing effectiveness by causing undesirable side effects.


More Information about Velasof Tablet

  • Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Velasof Tablet

Read the instructions carefully before taking Velasof tablet. Take them as directed by your doctor. Take it with or without food. This will help to improve absorption. If you experience side effects, stop taking them and talk to your doctor.


Safety Advices for

Pregnancy

There is limited information about the safety of Velasof tablet in pregnancy. If you are pregnant and considering taking them, talk to your doctor about the risks and benefits. They can help you decide if they are right for you.

Breast Feeding

There is limited information about the safety of Velasof tablet in breastfeeding. If you are pregnant or planning to become one, talk to your doctor about the risks and benefits. They can help you decide if they are right for you.

Lungs

If you have a chronic lung disease and are considering taking Velasof tablet, talk to your doctor about the risks and benefits.

Liver

If you have a chronic lung disease, talk to your doctor about the risks and benefits. They can help you decide if Velasof tablet is right for you.

Alcohol

It is generally recommended to avoid alcohol consumption during hepatitis C treatment, including Velasof tablet. Alcohol can potentially worsen liver damage and interfere with the effectiveness of the medication. It is best to consult with your healthcare provider regarding alcohol consumption during treatment.

Driving

Common side effects of Velasof tablet include headache, fatigue, and dizziness. Suppose you experience any of these side effects or other symptoms that may impair your ability to drive safely. In that case, you should refrain from driving or operating heavy machinery until you feel fully alert and capable.


What if you forget to take Velasof Tablet?

If you miss a dose of Velasof Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

Side Effects of Velasof Tablet

Velasof tablet cause some side effects like all medications, although not everyone will experience them.

Serious:

  • Hepatitis B reactivation
  • Severe allergic reactions

Common:

  • Headache
  • Fatigue
  • Nausea
  • Insomnia
  • Diarrhea
  • Itching (pruritus)
  • Decreased appetite
  • Muscle or joint pain
  • Rash
  • Dizziness

Word of Advice

Before initiating treatment, individuals should be screened for hepatitis B virus (HBV) infection due to the risk of HBV reactivation. Close monitoring of liver function and HBV DNA levels is necessary during and after treatment, particularly for those with a current or prior HBV infection. Additionally, potential drug interactions with other medications should be carefully evaluated, and healthcare providers should be informed about all current medications. Individuals taking amiodarone should be closely monitored for severe bradycardia (decreased heart rate) when co-administered with this medication. Dose adjustments are necessary for patients with severe renal impairment or end-stage renal disease. Assessing the potential impact on psychiatric health, especially in individuals with a history of psychiatric disorders, is necessary.


FAQs

Q 1. Can Velasof tablet cure hepatitis C in individuals with advanced liver disease or cirrhosis?

Velasof tablet has shown efficacy in treating hepatitis C in individuals with advanced liver disease or compensated cirrhosis. However, the response rate may vary, and close monitoring of liver function is important during and after treatment.

Q 2. Is it necessary to undergo regular blood tests while on Velasof tablet treatment?

Yes, regular blood tests are typically conducted during Velasof tablet treatment to monitor liver function, viral load, and treatment response. These tests help assess the effectiveness of the medication and ensure patient safety.

Q 3. Can Velasof tablet be used in patients with kidney disease?

Velasof tablet can be used in patients with mild to moderate kidney impairment without dose adjustment. However, patients with severe renal impairment or end-stage renal disease may require dose adjustments or alternative treatment options. It is important to discuss your kidney function with your healthcare provider to determine the most appropriate treatment plan.

Q 4. Can Velasof tablet be used in patients with HIV co-infection?

Velasof tablet is effective and safe in individuals with both hepatitis C and HIV co-infection. However, it is important to coordinate treatment with both infectious disease and HIV specialists to ensure proper management of both conditions.

Q 5. Can Velasof tablet cause weight gain or loss?

Weight gain or loss is not commonly reported as a side effect of Velasof tablet. However, individual responses to medication can vary. If you experience any unexplained or concerning changes in weight during treatment, it is recommended to consult your healthcare provider for further evaluation.

Q 6. Can Velasof tablet be used in patients with a history of liver transplantation?

Velasof tablet can be used in patients with a history of liver transplantation who have recurrent hepatitis C. However, individual patient factors and the specific post-transplantation period must be considered. Consultation with a transplant hepatologist or specialist is recommended to determine the most appropriate treatment approach.

Q 7. Can Velasof tablet cause any serious side effects?

While Velasof tablet is generally well-tolerated, like any medication, it can potentially cause side effects. Common side effects include headache, fatigue, nausea, and insomnia. Serious side effects are rare but can include severe allergic reactions, changes in heart rate, and liver problems. It is important to discuss any concerns or potential side effects with your healthcare provider, who can provide further information and guidance based on your specific situation.


Fact Box of Velasof Tablet

Molecule name: Sofosbuvir, Velpatasvir Therapeutic class: Antiviral
Pharmacological class:

1. Sofosbuvir: Nucleotide analog 

2. Velpatasvir: Direct-acting antiviral (DAA) 

Indications: Chronic hepatitis C (HCV) infection

 


References

  1. Gilead Sciences Ltd, Electronic medicines compendium (EMC), [Revised on Jan 2021] [ Accessed on 24th June 2023], https://www.medicines.org.uk/emc/files/pil.7294.pdf
  2. Gilead Sciences Inc, US Food and Drug Administration, [Revised on Aug 2017] [Accessed on 24th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208341s007lbl.pdf
  3. Sarah L Greig; Sofosbuvir/Velpatasvir: A Review in Chronic Hepatitis C; Drugs; [Published on 24th June 2023]; [Accessed on 24th June 2023]; https://pubmed.ncbi.nlm.nih.gov/27730529/
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Velasof Tablet

Velasof Tablet

₹20,855.00 Original price was: ₹20,855.00.₹5,999.00Current price is: ₹5,999.00.
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