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Vonaday Tablet
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Emcure

Vonaday Tablet

₹3,455.42 Original price was: ₹3,455.42.₹1,699.00Current price is: ₹1,699.00.

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  • Lamivudine (300mg)
  • Tenofovir disoproxil fumarate (300mg)
  •  Efavirenz (600mg)
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About Vonaday Tablet

Salt : Lamivudine (300mg) + Tenofovir disoproxil fumarate (300mg) + Efavirenz (600mg)

Product Introduction

Vonaday 300mg/300mg/600mg Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Vonaday 300mg/300mg/600mg Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach, preferably at bedtime for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine must not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.

The most common side effects of this medicine are impaired concentration, abnormal dreams, headache, nausea, weakness and fatigue, nasal congestion, diarrhea, rash, dizziness, trouble sleeping, pain, depression, and cough. These are usually not serious and go away within 2-4 weeks of treatment, however, inform your doctor if they bother you or do not go away. As it can also make you feel dizzy or drowsy, it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any kidney, liver, or other diseases. Your doctor may suggest some laboratory tests before and during the treatment to check your blood counts, liver and kidney functioning, and other health and mental conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods to prevent transmission of HIV during intercourse.


Uses of Vonaday Tablet

  • Treatment of HIV infection

Benefits of Vonaday Tablet

In Treatment of HIV infection

Vonaday 300mg/300mg/600mg Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.


Side effects of Vonaday Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Vonaday

  • Joint pain
  • Pneumonia
  • Muscle pain
  • Increased triglyceride level in blood
  • Elevated levels of serum amylase
  • Blood in urine
  • Increased transaminase level in blood
  • Cough
  • Impaired concentration
  • Abnormal dreams
  • Headache
  • Dizziness
  • Nausea
  • Insomnia (difficulty in sleeping)
  • Weakness
  • Depression
  • Diarrhea
  • Rash
  • Pain
  • Fever
  • Decreased white blood cell count (neutrophils)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Back pain
  • Abdominal pain
  • Anxiety
  • Vomiting
  • Indigestion

How to use Vonaday Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vonaday 300mg/300mg/600mg Tablet is to be taken empty stomach.

How Vonaday Tablet works

Vonaday 300mg/300mg/600mg Tablet is a combination of three antiviral medicines: Lamivudine, Tenofovir disoproxil fumarate and Efavirenz. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Safety advice

Pregnancy

Vonaday 300mg/300mg/600mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast Feeding

Vonaday 300mg/300mg/600mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Lungs

It is unknown whether Vonaday  tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Liver

Vonaday 300mg/300mg/600mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Vonaday 300mg/300mg/600mg Tablet may not be needed in these patients. Please consult your doctor.

Alcohol

Caution is advised when consuming alcohol with Vonaday 300mg/300mg/600mg Tablet. Please consult your doctor.

Driving

Vonaday 300mg/300mg/600mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.


What if you forget to take Vonaday Tablet?

If you miss a dose of Vonaday 300mg/300mg/600mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

  • Vonaday 300mg/300mg/600mg Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
  • Take it on an empty stomach, preferably at bedtime, to reduce side effects.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Vonaday 300mg/300mg/600mg Tablet may cause dizziness or sleepiness. Don’t drive or do anything requiring concentration until you know how it affects you.
  • Vonaday 300mg/300mg/600mg Tablet can cause birth defects. Use effective contraception while taking Vonaday 300mg/300mg/600mg Tablet and 12 weeks after stopping it.
  • It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Do not stop taking Vonaday 300mg/300mg/600mg Tablet without your doctor’s

Side Effects of Vonaday Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

  • Rapid breathing
  • Drowsiness
  • Nausea, vomiting, and stomach pain
  • Severe allergic reactions
  • Severe mood disturbances, depression, and suicidal thoughts
  • Confusion, forgetfulness, seizures, and tremor
  • Liver toxicity
  • Kidney damage
  • Autoimmune disorders

Common:

  • Bloating, flatulence
  • Headache
  • Sleeplessness
  • Skin reactions
  • Wheezing, swelling, or lightheadedness
  • Hair loss
  • Diarrhea
  • Bone disorders
  • Weakness
  • Anemia

Word of Advice

Inform your doctor about your underlying infections. If you have advanced HIV (AIDS), you may develop signs of infection and inflammation or worsen the signs of an existing infection once treatment is started. Report your doctor for side effects. It is mandatory to tell your medical professional if you are consuming other medicines that may damage your kidneys. Always consume the dose recommended by your doctor. Vonaday tablet does not reduce the risk of transmitting HIV to others via sexual contact or blood contamination. You must continue the medication to avoid this complication.


FAQs

Q 1. What should you not take with Vonaday tablet?

It is not recommended to take Vonaday tablet with other HIV medications. Tell your healthcare provider if you are taking other medications, over-the-counter drugs, vitamins, or herbal supplements.

Q 2. How can Vonaday Tablets be stored?

Store Vonaday tablets below 30°C in its original container, away from the reach of children.

Q 3. What should you do if you miss a dose of Vonaday Tablet?

If you missed a dose ofVonaday Tablet, take one tablet as soon as you remember. However, if it is almost time for your next dose, skip this dose and take your next dose as per schedule. Do not take two doses to compensate for the missed dose.

Q 4. What are the required laboratory parameters before taking Vonaday treatment?

If you are an adolescent or adult of childbearing potential, your healthcare provider will perform a pregnancy test before prescribing this treatment. Other prominent tests include HBV infection, serum creatinine, estimated creatinine clearance, urine glucose, and urine protein.

Q 5. How do you know if you are hypersensitive to Vonaday?

Watch out for symptoms like severe rash, Steven’s Johnsons syndrome, and swelling of the face or lips, and immediately reach out to your healthcare provider if you experience any of these symptoms.


Fact Box of Vonaday Tablet

Molecule name: Efavirenz, Lamivudine, Tenofovir disoproxil fumarate  Therapeutic class:  Antiretroviral 
Pharmacological class:

1. Nucleoside reverse transcriptase inhibitors (NRTIs)

2. Nonnucleoside reverse transcriptase inhibitors (NNRTIs)

Indications: Human Immunodeficiency Virus (HIV-1) infection

References

  1. Macleods Pharmaceuticals Limited, US Food and Drug Administration, [Revised on Mar 2019] [Accessed on 23rd Apr 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210649s000lbl.pdf
  2. Clinical info HIV.gov, Efavirenz / Lamivudine / Tenofovir Disoproxil Fumarate – Patient | NIH (hiv.gov)
  3. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
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Vonaday Tablet

Vonaday Tablet

₹3,455.42 Original price was: ₹3,455.42.₹1,699.00Current price is: ₹1,699.00.
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