Buy Trustiva Tablet Online
About Trustiva Tablet
Salt : Tenofovir disoproxil fumarate (300mg) + Efavirenz (600mg) + Emtricitabine (200mg)
Product Introduction
Trustiva Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.Common side effects of this medicine include nausea, vomiting, diarrhea, flatulence, trouble sleeping, headache, rash, sinusitis. These are usually not serious, however, inform your doctor if they bother you or do not go away. This medicine can also make you feel dizzy or drowsy, so it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects. While on the treatment, generally, some people may experience bone pain. To cope up with this you can take calcium and vitamin D supplements as per your doctor’s advice. Birth control pills are ineffective with this medicine, therefore other reliable birth controls should be used.Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any kidney, liver, or bone disease. Your doctor may suggest regular blood tests to check your blood counts, liver function, and kidney function. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.
Uses of Trustiva Tablet
- HIV infection
Benefits of Trustiva Tablet
In HIV infection
Trustiva Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.
It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.
Side effects of Trustiva Tablet
Common side effects of Trustiva
- Nausea
- Diarrhea
- Rash
- Decreased white blood cell count (neutrophils)
- Vomiting
- Abdominal pain
- Allergic reaction
- Fatigue
- Increased lipase in the blood
- Headache
- Insomnia (difficulty in sleeping)
- Depression
- Dizziness
- Abnormal dreams
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Upper respiratory tract infection
- Anxiety
- Sinus inflammation
How to use Trustiva Tablet
How Trustiva Tablet works
Safety Advices
Pregnancy
If you are pregnant or plan to become pregnant, it is crucial to consult with your healthcare provider before taking Trustiva Tablet.
Breast Feeding
Trustiva Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So patients should consult a doctor before taking it.
Lungs
Suppose you have a history of lung disease or are experiencing respiratory symptoms while taking it. Then it is important to consult the healthcare provider for a thorough evaluation before taking Trustiva Tablet.
Liver
The safety of Trustiva Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider.
Alcohol
It is generally recommended to avoid excessive alcohol consumption while taking Trustiva Tablet or any medication. Alcohol can interact with this medication and affect liver function.
Driving
Some people experience side effects, including dizziness, drowsiness, or fatigue, while taking Trustiva Tablet. Suppose anyone experiences any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery.
What if you forget to take Trustiva Tablet?
Quick tips
- Trustiva Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
- Take it on an empty stomach, preferably at bedtime, to reduce side effects.
- Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
- Trustiva Tablet may cause dizziness or sleepiness. Don’t drive or do anything requiring concentration until you know how it affects you.
- Trustiva Tablet can cause birth defects. Use effective contraception while taking Trustiva Tablet and 12 weeks after stopping it.
- It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
- Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
- Do not stop taking Trustiva Tablet without your doctor’s advice.
Side Effects of Trustiva Tablet
Trustiva Tablets cause side effects like all medications, although not everyone will experience them.
Serious:
- Kidney problems or renal toxicity
- Decreased bone mineral density or bone loss
- Lactic acidosis (a huge accumulation of lactic acid in the blood)
- Hepatic steatosis (fat accumulation in the liver)
- Immune reconstitution syndrome (a paradoxical worsening of pre-existing infections or inflammatory conditions when the immune system strengthens)
Common:
- Nausea
- Diarrhea
- Headache
- Fatigue
- Dizziness
- Insomnia
- Rash
Word of Advice
If you are considering taking Trustiva Tablet, knowing the potential risks and warnings associated with this medication is important. Pregnancy and breastfeeding require individual evaluation and consultation with a doctor to weigh the benefits against potential risks. It should be used cautiously in individuals with pre-existing conditions such as liver disease, kidney disease, or bone disorders, as it may exacerbate them. Close monitoring and appropriate management are necessary in these cases. Adherence to these precautions and regular monitoring and communication with the healthcare provider can help ensure safe and effective use.
FAQs
Q 1. Can Trustiva Tablet be taken with other antiretroviral medications?
Trustiva Tablet is often combined with other antiretroviral medications as part of a multidrug regimen for treating HIV infection. The specific combination of medications will depend on individual health status, treatment history, and potential drug interactions
Q 2. Can Trustiva Tablet be safely used by older adults?
Trustiva Tablet can be used in older adults. Still, dosage adjustments or additional monitoring may be necessary, as age-related changes in kidney and liver function can affect medication clearance. It is important to discuss individual health status and any concerns with a healthcare provider.
Q 3. Can Trustiva Tablet be used in individuals with pre-existing bone conditions?
Individuals with pre-existing bone conditions, such as osteoporosis or osteopenia, may require careful monitoring and management when using Trustiva Tablet. It is important to discuss any underlying bone conditions with your healthcare provider to ensure appropriate bone health monitoring and potential supplementation.
Q 4. Can Trustiva Tablet prevent all forms of HIV transmission?
Trustiva Tablet, when used as PrEP, significantly reduces the risk of HIV transmission through sexual activity or injection drug use. However, they do not provide 100% protection against HIV, and it is important to continue practicing safe sex and taking other preventive measures.
Q 5. Can Trustiva Tablet cause lactic acidosis?
Although rare, Trustiva Tablet has been associated with the risk of lactic acidosis. Lactic acidosis is a serious condition characterized by the accumulation of lactic acid in the blood. It is important to promptly report any symptoms such as unusual weakness, rapid breathing, nausea, vomiting, abdominal pain, or unexplained muscle pain to your healthcare provider while taking it.
Q 6. Can Trustiva Tablet prevent all forms of HIV transmission?
Trustiva Tablet, when used as PrEP, significantly reduces the risk of HIV transmission through sexual activity or injection drug use. However, they do not provide 100% protection against HIV, and it is important to continue practicing safe sex and taking other preventive measures.
Q 7. Can Trustiva Tablet cause lactic acidosis?
Although rare, Trustiva Tablet has been associated with the risk of lactic acidosis. Lactic acidosis is a serious condition characterized by the accumulation of lactic acid in the blood. It is important to promptly report any symptoms such as unusual weakness, rapid breathing, nausea, vomiting, abdominal pain, or unexplained muscle pain to your healthcare provider while taking it.
Q 8. Are any specific tests or monitoring required for bone health while taking Trustiva Tablet?
Monitoring of bone mineral density may be recommended for individuals on long-term treatment with Tenofovir disoproxil fumarate. Your healthcare provider may request bone density scans or blood tests to assess bone health and determine if any interventions or additional treatments are necessary.
Q 9. Can Trustiva Tablet be used in individuals with liver or kidney disease?
Trustiva Tablets should be used cautiously in individuals with liver or kidney impairment. Dose adjustments or alternative treatment options may be necessary.
Fact Box of Trustiva Tablet
| Molecule name: Emtricitabine and Tenofovir disoproxil fumarate | Therapeutic class: Antiviral agents |
| Pharmacological class: Nucleoside reverse transcriptase inhibitors (NRTIs) | Indications: HIV- 1 Infection |
References
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
- Tillomed Laboratories Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 19th May 2023], https://www.medicines.org.uk/emc/files/pil.11636.pdf
- Gilead Sciences, Inc, US Food and Drug Administration, [ Revised on March 2016] [ Accessed on 19th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021752s047lbl.pdf
-
. Dupont Merck. A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on June 2005] [Accessed 11th November 2020] https://clinicaltrials.gov/ct2/show/NCT00002227
5. Natella Y. Rakhmanina and John N. van den Anker. Efavirenz in the Therapy of HIV Infection. NCBI; PMC US National Library of Medicine, National Institute of Health. January 2011. [Accessed 11th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810555/
6. APL Swift Services (Malta) Limited or Milpharm Limited. Electronic Medicines Compendium (EMC); [Revised on April 2019] [Accessed 11th November 2020] https://www.medicines.org.uk/emc/files/pil.7070.pdf
7. Bristol-Myers Squibb S.r.l or Aesica Queenborough Limited. Electronic Medicines Compendium (EMC); [Revised on February 2019] [Accessed 11th November 2020] https://www.medicines.org.uk/emc/files/pil.7734.pdf
8. Pharmadox HeaIthcare Ltd. Electronic Medicines Compendium (EMC); [Revised on March 2019] [Accessed 11th November 2020] https://www.medicines.org.uk/emc/files/pil.2066.pdf
9. Generics [UK] Limited and Gerard Laboratories. Electronic Medicines Compendium (EMC); [Revised on September 2018] [Accessed 11th November 2020] https://www.medicines.org.uk/emc/files/pil.719.pdf
10. Bristol-Myers Squibb Company. U.S. Food & Drug Administration. [Revised on March 2016] [Accessed 11th November 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020972s049-021360s038lbl.pdf
