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Instgra Tablet
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Emcure

Instgra Tablet

₹3,563.00 Original price was: ₹3,563.00.₹2,299.00Current price is: ₹2,299.00.

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  • Dolutegravir (50mg)
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Description

Buy Instgra Tablet Online

About Instgra Tablet

Salt : Dolutegravir (50mg)

Product Introduction

Instgra Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It prevents the multiplication of viruses in human cells and clears up your infection.

Some common side effects include headache, insomnia (difficulty sleeping), dizziness, diarrhea, nausea, and fatigue. These are usually not serious but tell your doctor if they bother you or persist for a longer duration. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.


Uses of Tablet

  • HIV infection

Benefits of  Tablet

In HIV infection

Instgra Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.


Side effects of Instgra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of

  • Headache
  • Insomnia (difficulty in sleeping)
  • Dizziness
  • Diarrhea
  • Nausea
  • Fatigue
  • Muscle pain
  • Increased liver enzymes

How to use Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Instgra Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Instgra Tablet works

Tablet is an anti-HIV medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety advice

Pregnancy

Instgra Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast Feeding

Instgra Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Lungs

It is unknown whether Instgra 50mg Tablets can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Liver

Instgra Tablet should be used with caution in patients with liver disease. Dose adjustment of Instgra Tablet may be needed. Please consult your doctor.

Alcohol

Caution is advised when consuming alcohol with Instgra Tablet. Please consult your doctor.

Driving

Instgra Tablet may cause side effects which could affect your ability to drive.


What if you forget to take Tablet?

If you miss a dose of Instgra Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Quick tips

  • Take Instgra Tablet with or without food, preferably at the same time everyday.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Do not take antacids or calcium supplements an hour before or two hours after taking Instgra Tablet.
  • Your doctor may monitor your liver function regularly during treatment. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Side Effects of

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

  • Allergic reactions (swelling, high temperature)
  • Infection, inflammation
  • Inflammation of the liver; liver failure
  • Joint pain

Common

  • Depression
  • Abnormal dreams, insomnia
  • Itching, rash
  • Being sick
  • Stomach discomfort, pain
  • Headache
  • Diarrhea
  • Fatigue

Word of Advice

To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It’s necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything with body fluids or blood should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus.


FAQs

Q 1. What medicines should I avoid with theTablet?

It is necessary to make your healthcare provider aware of any medicines you take, including herbal, complementary, or other medicines you may buy from the pharmacy or online, to ensure they are compatible with Instgra 50mg Tablet and any other anti-HIV drugs you take.

Q 2. Who should not take a Instgra 50mg Tablet?

People with a previous allergic reaction or hypersensitivity to the Instgra 50mg Tablet or its components should not take this medication.

Q 3. Do I get hepatic impairment when taking this Instgra 50mg Tablet?

The liver metabolizes this drug, so individuals with severe hepatic impairment should avoid taking Instgra 50mg Tablets, and it is necessary to ask your physician to determine the appropriateness of this medicine in individuals with liver problems.

Q 4. How does Instgra 50mg Tablet work for HIV?

Instgra 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection.

Q 5. What if I miss my Instgra 50mg Tablet?

If you miss a dose of the Instgra 50mg Tablet or it is almost time for the next dose schedule, do not take it. Wait and take the next dose of this Tablet at its regular time.

Q 6. Can you consume alcohol during treatment with a Instgra 50mg Tablet?

It is highly not advised to consume alcohol while on treatment with a Instgra 50mg Tablet, as alcohol might affect how this medication works in your body.

Q 7. What are some of the long-term serious side effects of treatment with Instgra 50mg Tablet?

Some serious side effects of treatment with Instgra 50mg Tablet include worsening hepatitis B, bone loss, kidney injury, pancreatitis, immune reconstitution syndrome, liver toxicity, and hypersensitivity reactions.


Fact Box of Instgra 50mg Tablet 30’s

Molecule name: Dolutegravir Therapeutic class: Antiviral
Pharmacological class: Integrase strand transfer inhibitor Indications: Human Immunodeficiency Virus (HIV)

References

  1. Tivicay 10mg Tablets – patient information leaflet (PIL) – (EMC). [Revised on June 2022] Available at: https://www.medicines.org.uk/emc/files/pil.10057.pdf [Accessed 22 May 2023].
  2. ViiV Healthcare, U.S. Food & Drug Administration, [Revised on June 2020] [Accessed on 22 May 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213983s000lbl.pdf
  3. Bertram G Katzung, Basic and Clinical Pharmacology, Antiviral Agents, 14th Edition, 2017, 883.
  4. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Additional information
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Emcure

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Instgra Tablet

Instgra Tablet

₹3,563.00 Original price was: ₹3,563.00.₹2,299.00Current price is: ₹2,299.00.
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